Another nutrient combo against Alzheimer's
Recently I reported on the combination of Omega 3 and B vitamins that slashed brain shrinkage in humans. This shrinkage is directly correlated to dementia risk. [Ref: B Vitamins plus Omega 3 slash Dementia Risk by 70% - NutriShield]
Now comes an exciting new study on a combination of curcumin and EGCG, published in the prestigious Nature Scientific Reports in August 2023. It shows an equally remarkable result – albeit this time on mice – which are commonly used in this type of research. [Ref: Combination of epigallocatechin 3 gallate and curcumin improves d-galactose and normal-aging associated memory impairment in mice | Scientific Reports (nature.com)]
Colin Rose is a Senior Associate Member of the Royal Society of Medicine, and Fellow of the Royal Society of Arts.
He is the Founder and Director of Research and Innovation of Uni-Vite Healthcare and author of a recent book: Delay Ageing: Healthy to 100, where he reveals how to slow ageing and, therefore, help prevent later-life illness.
Combination is synergistic
It is well established that oxidative stress – also known as free radical damage – exerts wide-ranging damage on organs and tissues throughout the body and plays a key role in neuro-degeneration and dementia.
The nutrients curcumin and EGCG (EpiGalloCatechin-3-Gallate), a polyphenol that is especially abundant in green tea, have individually shown memory and general health benefits in both animal and human studies.
But what happens to brain health when you combine them?
The researchers ran behavioural tests on groups of young and aged mice. Both compounds effectively elevated memory function, including in healthy young controls. Curcumin alone was less effective than EGCG alone.
However, the effect of the combination of EGCG and curcumin on older mice resulted in a cognitive brain function that actually surpassed those of healthy young controls.
The researchers concluded:
“EGCG and curcumin combination could serve as a better choice in managing aging-related memory disorders”.
Adding astaxanthin gives a further boost
The researchers also found that astaxanthin, another powerful antioxidant, produced a similar cognitive boost. Astaxanthin is what gives salmon its pink hue and it is found mostly in seafood.
A 4-way combo?
Whilst no one has yet formally researched a four-way combination of Omega 3, B vitamins, plus curcumin and EGCG, anyone taking NutriShield Premium is already taking this combination!
I have taken NutriShield Premium every day for over 20 years, and although it’s a sample of one, I know from epigenetic testing that my brain age is many years younger than my chronological age of 83.
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