How Vitamin D cuts the risk of cancer

How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

Health Benefits of Vitamin D

As you’ll know, the NHS recommends that we all supplement with vitamin D specifically vitamin D3 in the winter to help boost our immune system against colds and flu. But there is another very important reason to take extra vitamin D.

Vitamin D is a vital factor in helping protect against cancer stem cells. Indeed, the NHS website quotes a large study from the National Cancer Center in Japan, that links higher vitamin D blood levels with significantly lower rates of cancer.

Every single day your immune system needs to combat about 10,000 cells that turn cancerous. Whether those cancer cells survive and begin to multiply to become a health threat depends on whether your immune system is strong and healthy.

Whether your immune system is strong and healthy in turn depends to an important extent on whether you have adequate vitamin D.

Yet health scientists warn that vitamin D deficiency is the most common nutritional deficiency today. Indeed almost 90% of the population in Northern Europe and North America are thought to have less than optimum vitamin D blood levels.

When you can ensure a safe and optimum vitamin D level for just 3p a day – that’s makes no sense.

This article was written by Colin Rose, a Senior Associate Member of the Royal Society of Medicine, who has been writing on science for 40 years.

10 ways Vitamin D3 will improve your health

Vitamin D is one of the most widely researched nutrients. We have done a systematic review of the literature and these studies – referenced at the end of this article – confirm the following.

(1) Vitamin D lowers the risk of colorectal cancer

The risk becomes less as the level of supplementation is increased – up to approximately 2,000 IU a day.

(2) Vitamin D reduces the risk of chronic infections

It does so by improving immune response.

(3) Vitamin D helps inhibit prostate cancer cells

It does this by supporting the increased production of a protein called GcMAF, which helps inhibit cancer cells growing in the prostate. GcMAF has a potent general anti-cancer effect that may reduce tumour size in as little as 10 days.

(4) Vitamin D activates macrophages which consume cancer cells

The same protein GcMAF activates components of the immune system called macrophages, whose function is to literally consume cancer and viral cells.

(5) Vitamin D reduces risk of breast and lung cancer

Vitamin D reduces the risk of breast cancer, probably by inhibiting
a gene that plays a role in breast cancer – a so-called oncogene (ie. a gene that carries the ability to cause cancer) called Her-2.

It also lowers the risk of lung cancer.

(6) Vitamin D is essential for calcium absorption and therefore strong bones

Vitamin D3 is also essential to ensure calcium absorption and hence helps produce strong bones. Sufficient Vitamin D3 cuts the risk of osteoporosis or osteomalacia (softening of bones).

(7) Vitamin D can activate 1,000 health-promoting genes

Overall, vitamin D as D3 – the natural form that is the same as created by sunlight – is able to activate almost 1,000 genes that contribute to health.

(8) Vitamin D reduces inflammation

Vitamin D helps reduce chronic inflammation in body tissues – and inflammation is a key driver of many long-term illnesses including heart disease, stroke and diabetes.

(9) Vitamin D improves SAD, mood and sleep quality

Vitamin D has been shown to improve general mood and sleep quality. A 2018 study links low vitamin D with a number of sleep disorders, and other studies implicate low vitamin D with S.A.D. – Seasonal Affective Disorder.

(10) Vitamin D improves brain function

People with a deficiency in vitamin D have less neuroprotection. Indeed, one study shows an almost 50% increased risk of decreased cognitive function when vitamin D is deficient.

Combine Vitamin D with Omega 3, Curcumin and Vitamin K for cancer protection

Although the foundation of health is always regular activity and a good diet, there are specific nutrients that are also known to help reduce the risk of cancer. They include:

  • Curcumin
  • Lycopene
  • The compound EGCG (epigallocatechingallate) found in green tea and green tea extract
  • Omega 3
  • Beta carotene
  • Lutein
  • Flavonoids – found in vegetables, fruits – especially the flavonoids in berries like bilberries and raspberries, and grapeseed.
  • Soy Isoflavones – associated with the lower levels of breast and prostate cancer in Japan.

The D-K combo

If you are supplementing with Vitamin D, make sure you are also taking a supplement with Vitamin K in it.  Or eating lots of high-vitamin-K foods, like kale and spinach.

How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals
Curly kale has over 1,000 mcg of Vitamin K per cup

That is because vitamin K ensures that calcium is absorbed and metabolised into bones where you want it and not deposited on artery walls – which could lead to arteries becoming harder, stiffer and less flexible.

Vitamin K is also a ‘co-factor’ with vitamin D, calcium and glucosamine to help restore connective tissue damaged in joint problems like arthritis. So, vitamins D and K are important to joint health.

Vitamins D3 and K2 – the ideal forms – are also important for heart health, helping prevent the build-up of plaque in arteries. Indeed, a study in 2004 showed that people with the highest intake of vitamin K had a 50% lower mortality risk than those with the lowest level.

Vitamin K is also produced in the gut by beneficial bacteria called probiotics. Therefore, a probiotic supplement can be a good way to ensure a healthy level of vitamin K.

Make curcumin bioavailable

How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

If you are supplementing with curcumin (from turmeric), ensure that the supplement includes both piperine (a black pepper extract), Omega 3 fatty acids and/or a fat like lecithin,because curcumin, whilst hugely beneficial, is not easily absorbed and these ingredients make it a lot more bioavailable.

Vitamin D has protective benefits beyond cancer

Finally, in a 2018 review, Medical News Today reported that:

“Studies are also suggesting that vitamin D might have protective benefits against heart failure, diabetes, cancer, respiratory tract infections, autoimmune disease, and even hair loss.”

How much Vitamin D is optimum?

It is important to get a safe, yet optimum, vitamin D3 supplement. Studies show that this is 2,000 IU or 50mcg a day. You can get a helpful free report on Vitamin D at https://nutrishield.com/download-pages/free-vitamin-d-ebook/

You can also buy vitamin D3 for less than 3p a day from here https://nutrishield.com/the-products/vitamin-d/


How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

This article was written by Colin Rose, a Senior Associate Member of the Royal Society of Medicine, who has been writing on science for 40 years.


If you found this article helpful and believe it can help others who are concerned to help prevent cancer, then please share it. You can also follow me through the icons below.

How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and MineralsHow Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and MineralsHow Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

PS. A “best of the best” eating plan

We said that the foundation for health is a really good diet. Click here for a summary of the ‘best of the best’ taken from the largest prestige university scale studies. https://nutrishield.com/wp-content/uploads/2019/10/CR-News-Food-table.pdf


How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals
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How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

Dr Paul Clayton designed NutriShield as a comprehensive health supplement with OPTIMUM levels of essential nutrients. See more detail elsewhere on this site or click on the button.


How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

Dr Paul Clayton’s best-selling book Health Defence is available from booksellers.

Read it here online or see the website www.healthdefence.com for excerpts and links to buy direct from the publisher.


How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

See online here for delicious recipes from the Health Defence Cookbook incorporating healthy foods featuring in a Mediterranean Diet.


References:

https://www.nhs.uk/news/cancer/vitamin-d-may-reduce-risk-some-cancers/

Plasma 25-hydroxyvitamin D concentration and subsequent risk of total and site specific cancers in Japanese population: large case-cohort study within Japan Public Health Center-based Prospective Study cohort BMJ 2018; 360 doi: https://doi.org/10.1136/bmj.k671 (Published 07 March 2018)

Clinical experience of integrative cancer immunotherapy with GcMAF. Inui T et al; Anticancer Res. 2013 Jul;33(7):2917-9.

Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside: Ehsan Saburi, Caspian. J Intern Med. 2017 Autumn; 8(4): 228–238.

Vitamin K2 enhances osteocalcin accumulation in the extracellular matrix of human osteoblasts in vitro. Koshihara Y, Hoshi K. J Bone Miner Res. 1997 Mar;12(3):431-8. PMID: 9076586

Absolute risk for fracture and WHO guideline. Pharmacological intervention to prevent osteoporotic fractures in the elderly. Clin Calcium. 2007 Jul;17(7):1098-104. PMID: 17607078

The Association between Vitamin D Deficiency and Sleep Disorders: A Systematic Review and Meta-Analysis. Qi Gao; Nutrients 2018 Oct; 10(10): 1395.

Seyama Y, Wachi H. Atherosclerosis and matrix dystrophy. J Atheroscler Thromb. 2004;11(5):236-45. PMID: 15557705

Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. Geleijnse JM, et al; J Nutr. 2004 Nov;134(11):3100-5. PMID: 15514282

Optimal serum 25-hydroxyvitamin D levels for multiple health outcomes. Bischoff-Ferrari HA; Adv Exp Med Biol. 2008;624:55-71. doi: 10.1007/978-0-387-77574-6_5.


Nutrition can help depression

University research shows that certain health supplements and combinations of foods and nutrients can not only improve overall mood but even reduce the incidence, length and severity of depression.

Omega 3

Nutrition can help depression NutriShield Multi Vitamins and MineralsPeople who are deficient in omega-3 fatty acids are generally more susceptible to depression and low mood. The brain has a high component of fatty acids and about 30% of these are Omega 3, according to the Mental Health Foundation. Intake of Omega 3 assists the production of dopamine –  the ‘reward’ neurotransmitter that responds to pleasurable experiences. Walnuts are a good source of plant-based Omega 3, but the body metabolises plant omega 3 less efficiently than fish oil.

Curcumin

Nutrition can help depression NutriShield Multi Vitamins and MineralsThe health benefits of curcumin (derived from turmeric) are well documented and wide ranging. It’s known to be an anti-inflammatory, has anti-cancer properties and is neuroprotective. But research published by The US National Institutes of Health now indicates it may even be as effective as Prozac (fluoxetine) – but without the side effects.

Their conclusion: “This study provides first clinical evidence that curcumin may be used as an effective and safe modality for treatment in patients with MDD [major depressive disorder] without concurrent suicidal ideation or other psychotic disorders.”

Selenium

Studies at the University of Wales have shown that people who are low in selenium have increased rates of depression, anxiety and tiredness and that optimising selenium intake helps raise mood and reduce depression.

Chromium

Chromium is a trace mineral involved in the regulation of insulin and thus metabolism. It has an important role in raising the brain’s level of serotonin and melatonin which help the brain regulate emotion, mood and sleep. Research at Duke University in the US has found that supplementation helps in the treatment of depression.

Magnesium

Magnesium has an important role in the development of serotonin, which is a major contributor to feelings of happiness. Researchers in Austin, Texas have shown that supplementation contributes to an improvement in mood and a reduction in depression.

Vitamin D

Nutrition can help depression NutriShield Multi Vitamins and MineralsIf there ever was a super-nutrient, it is surely vitamin D. Most people are depleted in Vitamin D, especially in the 5 months of winter. In addition to its role in supporting the production of healthy cells and a strong immune system, a major study at the Chicago School of Nursing has shown that Vitamin D supplementation improves mood and reduces depression. Their conclusion?

… Treatment of inadequate vitamin D levels in persons with depression and other mental disorders may be an easy and cost-effective therapy which could improve patients’ long-term health outcomes as well as their quality of life”.

Zinc

Zinc is a vital trace mineral needed for a strong immune system. In addition, Canadian researchers have found that it can help treat depression.

Vitamin B6

Researchers in a large UK hospital have successfully used vitamin B6 in the treatment of PMS depression. B6 is essential in regulating general brain function.

Folic Acid/Folate

Nutrition can help depression NutriShield Multi Vitamins and MineralsFolate, the B vitamin found in leafy green vegetables, assists in the regulation of serotonin and the neurotransmitter acetylcholine. They are both important in the passing of messages between brain cells. Researchers at the Neuropsychiatric Research Laboratory in Surrey have combined folic acid and vitamin B12 to help treat depression. Folate or folic acid may also increase the effectiveness of the anti-depressant fluoxetine.

Tryptophan

Nutrition can help depression NutriShield Multi Vitamins and MineralsThe amino acid tryptophan – in conjunction with vitamin B6 – raises the level of the hormone serotonin, which in turn helps elevate your mood. Deficiencies in B6 can cause a lowering of immune function and depression. Bananas not only contain tryptophan but vitamin B6, and fibre.  Fibre helps ensure that energy is slowly released into the bloodstream, so it helps keep your blood sugar and mood stable. The opposite is a ‘sugar rush’ where blood sugar levels rise but then dip quickly, leaving you feeling irritable.

Other foods that are above average in tryptophan are chicken and turkey.

Lentils, oats and whole grains

These are complex carbohydrates which have a low GI (Glycaemic Index), which helps stabilise your blood sugar levels and therefore mood.

Dark chocolate

Nutrition can help depression NutriShield Multi Vitamins and MineralsIn a recent study, 30 people were given just 40g of dark chocolate a day, over 14 days. They produced less stress hormones and their anxiety levels decreased. A small square of dark chocolate contains polyphenols which cause the brain to release endorphins and boost serotonin levels.

Calcium

A study in the Journal of the American College of Nutrition linked higher calcium intake to lower levels of PMS-related depression. This makes sense as (o)estrogen plays a significant role in calcium production. There was no indication, however, that increased calcium had any effect on male moods.

Saffron

Nutrition can help depression NutriShield Multi Vitamins and MineralsIn an innovative study at Tehran University of Medical Sciences, 50 women with PMS were given just 15 mg of saffron daily over two menstrual cycles.  By the end of the study, over three-quarters of the women reported that their PMS symptoms (such as mood swings and depression) declined by at least half, compared with only 8 percent of women in the placebo group.

Green tea

Green tea contains high levels of the amino acid theanine, which has been shown to be an anti-stress relaxant.

Conclusion – Mediterranean Diet plus supplement

I am conscious that if you suffer from depression or just want to boost your general mood, a list like this can be both encouraging but also a bit confusing.

But the overall conclusion is that there is evidence from many clinical trials that a largely Mediterranean Diet supported by a supplement that safely increases your intake of curcumin, Omega 3, vitamin D3, B vitamins, folic acid, zinc, chromium, selenium and green tea extract is very likely to help.

NutriShield contains all these nutrients at effective levels.

 


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Dr Paul Clayton designed NutriShield as a comprehensive healthNutrition can help depression NutriShield Multi Vitamins and Minerals supplement with OPTIMUM levels of essential nutrients. See more detail elsewhere on this site or click on the button.

Nutrition can help depression NutriShield Multi Vitamins and MineralsDr Paul Clayton’s best-selling book Health Defence is available from most good bookstores. See the website www.healthdefence.com for excerpts and links to buy direct from the publisher.

See online here for delicious recipes from the Health Defence Cookbook  incorporating healthy foods featuring in a Mediterranean Diet. Nutrition can help depression NutriShield Multi Vitamins and Minerals


REFERENCES

Sanmukhani J, Satodia V, Trivedi J, Patel T, Tiwari D, Panchal B, Goel A, Tripathi CB. Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial. Phytother Res. 2014 Apr;28(4):579-85. doi: 10.1002/ptr.5025. Epub 2013 Jul 6.

Benton D. Selenium intake, mood and other aspects of psychological functioning. Nutritional Neuroscience 2002

Haag, M. Department of Physiology, University of Pretoria, South Africa. Essential fatty acids and the brain. Canadian Journal of Psychiatry 2003, 2003 Apr; 48(3):195-203

Jacka, F.N., Pasco, J.A., Mykletun, A., et al. Association of Western and traditional diets with depression and anxiety in women.  Department of Clinical and Biomedical Sciences, University of Melbourne, Australia. American Journal of Psychiatry, 2010 Mar; 167(3):305-11

Kemper, K., Shannon, S. Pediatric Complementary and Alternative Medicine (CAM) Therapies to Promote Healthy Moods. Clinics of North America, 2007 December; 54(6): 901–926

Sue Penckofer, PhD, RN, Joanne Kouba, PhD, RD, Mary Byrn, BSN, RN, and Carol Estwing Ferrans, PhD, RN, FAAN. Vitamin D and Depression: Where is all the Sunshine? Ment Health Nurs. 2010 Jun; 31(6): 385–393.doi:  10.3109/01612840903437657

Thys-Jacobs S. Metabolic Bone Micronutrients and the premenstrual syndrome: the case for calcium. Center, St. Luke’s-Roosevelt Hospital Center, Columbia University, New York, New York. Journal of the American College of Nutrition, 2000 Apr; 19 (2):220-7

Docherty, J.P., Sack, D.A., Roffman, M. et al. Effectiveness of chromium in atypical depression: a placebo-controlled trial. Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, North Carolina. Biological Psychiatry, 2003 Feb 1; 53(3):261-4

Coppen, A., Bolander-Gouaille, C. Treatment of depression: time to consider folic acid and vitamin B12. MRC Neuropsychiatric Research Laboratory, Surrey, UK. Journal of Psychopharmacology, 2005 Jan; 19(1):59-65

Coppen A, Bailey J. Enhancement of the antidepressant action of fluoxetine by folic acid: a randomized, placebo controlled trial. Journal of Affect Disorders. 2000 Nov; 60(2):121–130

Conklin, S.M., Harris, J.I., Manuck, S.B., et al. Serum omega-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteers.  Cardiovascular Behavioral Medicine Postdoctoral Training Program, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA. Psychiatry Research, 2007 Jul 30; 152(1):1-10

Wyatt, K.M., Dimmock, P.W., Jones, P.W. Efficacy of vitamin B-6 in the treatment of PMS. Academic Department of Obstetrics and Gynecology, North Staffordshire Hospital. BMJ, 1999 May 22’318 (7195): 1375-81

Eby, G.A., Eby, K.L. Magnesium for treatment-resistant depression: a review and hypothesis. George Eby Research Institute, Austin, Texas. Medical Hypotheses. 2010 Apr;74(4):649-60

Milaneschi, Y., Hoogendijk, W., Lips, P., et al. The association between low vitamin D and depressive disorders. Department of Psychiatry and EMGO Institute for Health and Care Research and Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands. Molecular Psychiatry 2013 Apr 9

Swardfager, W., Herrmann, N., McIntyre, R.S., et al. Potential roles of zinc in the pathophysiology and treatment of major depressive disorder. Neuropharmacology Research Group, Sunnybrook Research Institute, Toronto, Canada. Neuroscience and Bio-behavioral Review 2013 Jun;37(5):911-29