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Plant flavonoids help prevent cancer and heart disease

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Study reveals powerful health-protective fruit and vegetable nutrients

One obvious way to live healthier for longer is to avoid heart disease and cancer.

The Edith Cowan University in Australia just issued an analysis of the diets of more than 53,000 Danish people over a 23-year period. They found that people who regularly ate foods rich in flavonoids had a significantly lower risk of dying from heart disease or cancer. The protective effect was even strong for those who smoked or drank too much.

This article was written by Colin Rose, a Senior Associate Member of the Royal Society of Medicine, who has been writing on science for 40 years.

Flavonoids and carotenoids – anti-oxidant and anti-inflammatory

Flavonoids are a group of plant compounds found in fruits and vegetables that confer health benefits through their antioxidant and anti-inflammatory effect. This improves blood vessel function – hence the reduction of heart attack risk.

A sub-group of flavonoids – the carotenoids like lycopene, lutein and beta carotene – also help ensure normal ‘cell signalling’. Cells need to signal or communicate their boundaries to prevent encroaching on neighbouring cells. If this communication breaks down, it can lead to cancer.

It is particularly helpful that the analysis was able to measure the daily level of flavonoids that create the protective effect and the lowest risk of heart disease and cancer.

That protective level was 500 mg of total flavonoids.

The many flavonoids

Flavonoids are as important to health as vitamins and minerals. There are a substantial number of flavonoids (which are in turn a class of plant compounds called polyphenols), including:

Flavonones

Found in eg. grapefruits, lemons, oranges.

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Anthocyanidins

Found eg. in strawberries, raspberries, blueberries, cherries, red wine.

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Flavones

Found in eg. peppers, celery, apples, parsley

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Isoflavones

Found in especially in soy. Particularly strong anti-cancer properties. And act as plant oestrogens.

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Flavonols

Found eg. in onions, kale, broccoli, leeks, grapes

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Flavanols

Different from flavonols, this class of flavonoid includes the catechins in green tea. Dark chocolate contains cocoa flavanols.

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Carotenoids

Colourants in the skins of plants.

Lycopene is the red in the skin of tomatoes.

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Lutein is in leafy green and yellow vegetables and egg yolks.

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Beta carotene is in carrots, peppers, apricots.

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Getting 500mg a day of flavonoids

The food chart at the end of this article answers the question of exactly how to get 500mg of flavonoids a day. It is based on a combination of the Mediterranean Diet and the DASH Diet – the latter stands for Dietary Approaches to Stop Hypertension. 

It’s called the MIND Diet because, in addition to incorporating the foods that best protect against heart disease, stroke, and cancer, it also includes foods and nutrients that help reduce the risk of Alzheimer’s.

Flavonoids also protect against dementia

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

The brain is a fatty organ – and researchers have shown that oxidation of the fats which form protective sheaths round neurons in the brain is a contributory cause of dementia. This oxidation is also known as
“free radical damage”.

Anti-oxidants counteract this oxidation and help prevent and slow that damage.

Inflammation in the brain is another contributory cause. So anti-inflammatory nutrients like flavonoids can help prevent inflammation damage.

Other research shows that carotenoids also help prevent the formation of the beta amyloid plaques and tangles that degrade neuron brain cells and characterise an Alzheimer’s brain.

Furthermore, the MIND Diet is also a natural immune system booster. It’s high in vitamins and minerals like vitamins A, C and D and zinc, plus Omega 3, as well as flavonoids and carotenoids. All of these nutrients strongly support the immune system.

The best of the best food plan

Even the MIND Diet can be improved, by including the best from the Japanese diet (like green tea and soy isoflavones) and one or two other nutrients – notably curcumin from the curry spice turmeric.

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Recent research shows that curcumin may help prevent the accumulation of plaques that build up in the brains of Alzheimer’s patients – and which interfere with communication between brain cells.

Indeed, curcumin activates hundreds of genes that are anti-inflammatory and neuro (brain) protective.

Add a multi-nutrient supplement

Finally, you’ll notice that the food plan includes a multi-nutrient supplement called NutriShield. Because, if you’re trying to get all the nutrients you need, at the level you need, by eating only regular food, you may find it difficult.

That’s because the number of daily portions of fruits and vegetables in the MIND studies is considerably higher than a simple 5-a-day recommendation.

Both the American Cancer Society and University College London have concluded that the ideal intake is 9-10 portions of fruits and vegetables a day – plus 2-3 portions of oily fish a week.

At these levels, your intake of vitamins, minerals and flavonoids and other nutrients ensures that your blood chemistry becomes seriously protective against age-related illness generally.

NutriShield fills in the gap between an ideal and a realistic diet that most people can manage. It includes vitamins, minerals, 500 mg in total of mixed flavonoids, Omega 3, CoQ10 and glucosamine.

You can download the best of the best food plan free here.  https://nutrishield.com/wp-content/uploads/2018/03/CR-News-Food-table.pdf


Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

This article was written by Colin Rose, a Senior Associate Member of the Royal Society of Medicine, who has been writing on science for 40 years.


If you found this article helpful and believe it can help others who are concerned to help prevent heart disease, cancer and dementia, then please share it. You can also follow me through the icons below.

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and MineralsPlant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and MineralsPlant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals
Register now for a free monthly e-newsletter on the latest in nutrition and health research.


Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Dr Paul Clayton designed NutriShield as a comprehensive health supplement with OPTIMUM levels of essential nutrients. See more detail elsewhere on this site or click on the button.


Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

Dr Paul Clayton’s best-selling book Health Defence is available from booksellers.

Read it here online or see the website www.healthdefence.com for excerpts and links to buy direct from the publisher.


Plant flavonoids help prevent cancer and heart disease NutriShield Multi Vitamins and Minerals

See online here for delicious recipes from the Health Defence Cookbook incorporating healthy foods featuring in a Mediterranean Diet.


References

Flavonoid intake is associated with lower mortality in the Danish Diet Cancer and Health Cohort: Nicola P. Bondonno, Frederik Dalgaard, Cecilie Kyrø, Kevin Murray, Catherine P. Bondonno, Joshua R. Lewis, Kevin D. Croft, Gunnar Gislason, Augustin Scalbert, Aedin Cassidy, Anne Tjønneland, Kim Overvad, Jonathan M. Hodgson.  Nature Communications, 2019; 10 (1) DOI: 10.1038/s41467-019-11622-x

https://lpi.oregonstate.edu/mic/dietary-factors/phytochemicals/flavonoids

Protection by Flavanol-Rich Foods Against Vascular Dysfunction and Oxidative Damage: 27th Hohenheim Consensus Conference.  Helmut Sies, Peter C.H. Hollman, Tilman Grune, Wilhelm Stahl, Hans K. Biesalski, Gary Williamson;  Advances in Nutrition, Volume 3, Issue 2, March 2012, Pages 217–221

How Vitamin D cuts the risk of cancer

How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

Health Benefits of Vitamin D

As you’ll know, the NHS recommends that we all supplement with vitamin D specifically vitamin D3 in the winter to help boost our immune system against colds and flu. But there is another very important reason to take extra vitamin D.

Vitamin D is a vital factor in helping protect against cancer stem cells. Indeed, the NHS website quotes a large study from the National Cancer Center in Japan, that links higher vitamin D blood levels with significantly lower rates of cancer.

Every single day your immune system needs to combat about 10,000 cells that turn cancerous. Whether those cancer cells survive and begin to multiply to become a health threat depends on whether your immune system is strong and healthy.

Whether your immune system is strong and healthy in turn depends to an important extent on whether you have adequate vitamin D.

Yet health scientists warn that vitamin D deficiency is the most common nutritional deficiency today. Indeed almost 90% of the population in Northern Europe and North America are thought to have less than optimum vitamin D blood levels.

When you can ensure a safe and optimum vitamin D level for just 3p a day – that’s makes no sense.

This article was written by Colin Rose, a Senior Associate Member of the Royal Society of Medicine, who has been writing on science for 40 years.

10 ways Vitamin D3 will improve your health

Vitamin D is one of the most widely researched nutrients. We have done a systematic review of the literature and these studies – referenced at the end of this article – confirm the following.

(1) Vitamin D lowers the risk of colorectal cancer

The risk becomes less as the level of supplementation is increased – up to approximately 2,000 IU a day.

(2) Vitamin D reduces the risk of chronic infections

It does so by improving immune response.

(3) Vitamin D helps inhibit prostate cancer cells

It does this by supporting the increased production of a protein called GcMAF, which helps inhibit cancer cells growing in the prostate. GcMAF has a potent general anti-cancer effect that may reduce tumour size in as little as 10 days.

(4) Vitamin D activates macrophages which consume cancer cells

The same protein GcMAF activates components of the immune system called macrophages, whose function is to literally consume cancer and viral cells.

(5) Vitamin D reduces risk of breast and lung cancer

Vitamin D reduces the risk of breast cancer, probably by inhibiting
a gene that plays a role in breast cancer – a so-called oncogene (ie. a gene that carries the ability to cause cancer) called Her-2.

It also lowers the risk of lung cancer.

(6) Vitamin D is essential for calcium absorption and therefore strong bones

Vitamin D3 is also essential to ensure calcium absorption and hence helps produce strong bones. Sufficient Vitamin D3 cuts the risk of osteoporosis or osteomalacia (softening of bones).

(7) Vitamin D can activate 1,000 health-promoting genes

Overall, vitamin D as D3 – the natural form that is the same as created by sunlight – is able to activate almost 1,000 genes that contribute to health.

(8) Vitamin D reduces inflammation

Vitamin D helps reduce chronic inflammation in body tissues – and inflammation is a key driver of many long-term illnesses including heart disease, stroke and diabetes.

(9) Vitamin D improves SAD, mood and sleep quality

Vitamin D has been shown to improve general mood and sleep quality. A 2018 study links low vitamin D with a number of sleep disorders, and other studies implicate low vitamin D with S.A.D. – Seasonal Affective Disorder.

(10) Vitamin D improves brain function

People with a deficiency in vitamin D have less neuroprotection. Indeed, one study shows an almost 50% increased risk of decreased cognitive function when vitamin D is deficient.

Combine Vitamin D with Omega 3, Curcumin and Vitamin K for cancer protection

Although the foundation of health is always regular activity and a good diet, there are specific nutrients that are also known to help reduce the risk of cancer. They include:

  • Curcumin
  • Lycopene
  • The compound EGCG (epigallocatechingallate) found in green tea and green tea extract
  • Omega 3
  • Beta carotene
  • Lutein
  • Flavonoids – found in vegetables, fruits – especially the flavonoids in berries like bilberries and raspberries, and grapeseed.
  • Soy Isoflavones – associated with the lower levels of breast and prostate cancer in Japan.

The D-K combo

If you are supplementing with Vitamin D, make sure you are also taking a supplement with Vitamin K in it.  Or eating lots of high-vitamin-K foods, like kale and spinach.

How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals
Curly kale has over 1,000 mcg of Vitamin K per cup

That is because vitamin K ensures that calcium is absorbed and metabolised into bones where you want it and not deposited on artery walls – which could lead to arteries becoming harder, stiffer and less flexible.

Vitamin K is also a ‘co-factor’ with vitamin D, calcium and glucosamine to help restore connective tissue damaged in joint problems like arthritis. So, vitamins D and K are important to joint health.

Vitamins D3 and K2 – the ideal forms – are also important for heart health, helping prevent the build-up of plaque in arteries. Indeed, a study in 2004 showed that people with the highest intake of vitamin K had a 50% lower mortality risk than those with the lowest level.

Vitamin K is also produced in the gut by beneficial bacteria called probiotics. Therefore, a probiotic supplement can be a good way to ensure a healthy level of vitamin K.

Make curcumin bioavailable

How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

If you are supplementing with curcumin (from turmeric), ensure that the supplement includes both piperine (a black pepper extract), Omega 3 fatty acids and/or a fat like lecithin,because curcumin, whilst hugely beneficial, is not easily absorbed and these ingredients make it a lot more bioavailable.

Vitamin D has protective benefits beyond cancer

Finally, in a 2018 review, Medical News Today reported that:

“Studies are also suggesting that vitamin D might have protective benefits against heart failure, diabetes, cancer, respiratory tract infections, autoimmune disease, and even hair loss.”

How much Vitamin D is optimum?

It is important to get a safe, yet optimum, vitamin D3 supplement. Studies show that this is 2,000 IU or 50mcg a day. You can get a helpful free report on Vitamin D at https://nutrishield.com/download-pages/free-vitamin-d-ebook/

You can also buy vitamin D3 for less than 3p a day from here https://nutrishield.com/the-products/vitamin-d/


How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

This article was written by Colin Rose, a Senior Associate Member of the Royal Society of Medicine, who has been writing on science for 40 years.


If you found this article helpful and believe it can help others who are concerned to help prevent cancer, then please share it. You can also follow me through the icons below.

How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and MineralsHow Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and MineralsHow Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

PS. A “best of the best” eating plan

We said that the foundation for health is a really good diet. Click here for a summary of the ‘best of the best’ taken from the largest prestige university scale studies. https://nutrishield.com/wp-content/uploads/2019/10/CR-News-Food-table.pdf


How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals
Register now for a free monthly e-newsletter on the latest in nutrition and health research.


How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

Dr Paul Clayton designed NutriShield as a comprehensive health supplement with OPTIMUM levels of essential nutrients. See more detail elsewhere on this site or click on the button.


How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

Dr Paul Clayton’s best-selling book Health Defence is available from booksellers.

Read it here online or see the website www.healthdefence.com for excerpts and links to buy direct from the publisher.


How Vitamin D cuts the risk of cancer NutriShield Multi Vitamins and Minerals

See online here for delicious recipes from the Health Defence Cookbook incorporating healthy foods featuring in a Mediterranean Diet.


References:

https://www.nhs.uk/news/cancer/vitamin-d-may-reduce-risk-some-cancers/

Plasma 25-hydroxyvitamin D concentration and subsequent risk of total and site specific cancers in Japanese population: large case-cohort study within Japan Public Health Center-based Prospective Study cohort BMJ 2018; 360 doi: https://doi.org/10.1136/bmj.k671 (Published 07 March 2018)

Clinical experience of integrative cancer immunotherapy with GcMAF. Inui T et al; Anticancer Res. 2013 Jul;33(7):2917-9.

Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside: Ehsan Saburi, Caspian. J Intern Med. 2017 Autumn; 8(4): 228–238.

Vitamin K2 enhances osteocalcin accumulation in the extracellular matrix of human osteoblasts in vitro. Koshihara Y, Hoshi K. J Bone Miner Res. 1997 Mar;12(3):431-8. PMID: 9076586

Absolute risk for fracture and WHO guideline. Pharmacological intervention to prevent osteoporotic fractures in the elderly. Clin Calcium. 2007 Jul;17(7):1098-104. PMID: 17607078

The Association between Vitamin D Deficiency and Sleep Disorders: A Systematic Review and Meta-Analysis. Qi Gao; Nutrients 2018 Oct; 10(10): 1395.

Seyama Y, Wachi H. Atherosclerosis and matrix dystrophy. J Atheroscler Thromb. 2004;11(5):236-45. PMID: 15557705

Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. Geleijnse JM, et al; J Nutr. 2004 Nov;134(11):3100-5. PMID: 15514282

Optimal serum 25-hydroxyvitamin D levels for multiple health outcomes. Bischoff-Ferrari HA; Adv Exp Med Biol. 2008;624:55-71. doi: 10.1007/978-0-387-77574-6_5.