Nicotinamide Riboside April 23 study confirms anti-ageing Vitamin

Latest meta-survey on anti-ageing NAD+

The latest meta-survey study on NAD+ was published in April 2023 in the Journals of Gerontology.

The survey summarised some 21 studies – most of which were conducted between 2019 to 2022 – so this is NEW science.

The authors caution that, whilst most human studies so far are quite small scale, and not all studies gave consistent results, they were able to conclude that "... ageing and many disease states are associated with declines in NAD+ levels."

[Ref Dietary Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future Directions | The Journals of Gerontology: Series A | Oxford Academic (oup.com)]

What the meta survey authors say

"Aging and many disease states are associated with declines in nicotinamide adenine dinucleotide (NAD+) levels.

"Preclinical studies suggest that boosting NAD+ abundance with precursor compounds, such as nicotinamide riboside ... has profound effects on physiological function in models of aging and disease.

“Supplementation with these compounds is safe, tolerable, and can increase the abundance of NAD+."

And more ...

"Numerous diseases are associated with reduced NAD+ levels, including metabolic disorders, cancer, and neurodegenerative diseases. The potential benefits of restoring tissue and cellular NAD+ abundance back to young, healthy concentrations on physiological function with aging remain a prevailing question in biomedical research.

"Promising preclinical findings indicate that increasing NAD+ abundance is causally linked to improvements in physiological function and select markers of health span."

Our own conclusions about boosting NAD+ - YES!

We introduced our own NR+A because the research shows that oral supplementation with Nicotinamide Riboside increases NAD+ levels in blood cells by approximately 60%.

This translates to improvements in mitochondrial function and reductions in oxidative stress, DNA-damage pathways, and inflammation. It doesn’t necessarily mean you are going to feel far more energetic – the effect is more on cell vitality and therefore long term improved metabolic and mitochondrial health.

Chronic inflammation is a hallmark of ageing and many age-associated diseases.

Although NutriShield Premium, on its own, continues to be our most powerful anti-inflammatory formula, we believe that NR+A is a valuable addition because by boosting NAD+ levels and therefore mitochondrial function, it helps reduce inflammation.

More positive confirmation from top scientist in Harper's Bazaar magazine

Dr Nichola Conlon is a molecular biologist and expert in healthy ageing. Interviewed in Harper’s Bazaar in July 2023, she stated that:

“Scientists have demonstrated that boosting NAD+ back to youthful levels can rejuvenate old cells back to a state of youth, leading to multiple beneficial effects against ageing and age-related disease.”

Asked about Nicotinamide Riboside supplements, she added:

“... Notable results so far include improvements in cardiovascular function, reduced inflammation, improved cellular energy production, and reversal of biomarkers of ageing.”

Dr Conlon went on to suggest that NAD+ precursor supplements also help regulate circadian rhythm and improve sleep.

In a video interview, she said NAD+ supplementation might help women through the menopause – a benefit that is new to us.

Delay Ageing book explains the ageing process and how you can postpone it

Medical researchers agree that if you slow ageing, you also delay the onset of age-related disease. And we know that it’s not just nutrition. Sleep, reducing stress and cardio and strength exercise are also essential to longevity and ageing well.

My book Delay Ageing: Healthy to 100, published in 2020, explains the latest ageing science in an accessible way.

It’s been rated 5-star and I am sure you will get a lot of benefit from it, as so many have already.

Click here to go to the publisher's website where you can buy the printed book or Kindle version.